URGENT/BREAKING: UPDATED SUMMATION: The Spike Protein of SARS-CoV-2 is “Delivered” to All Organs via the Endothelium and Induces Systemic Nonsense mRNA Translations Resulting in Hyperaccelerated Aging

The Spike Protein, in Essence, Acts as a Progeria Drug

Since the appearance of the SARS-CoV-2 Spike Protein, the world has been stunned and puzzled by the increase in sudden deaths and dramatically increased excess mortality which continues to accelerate with each passing year. Curiously, there is a plethora of causes for these excess deaths. It is not just a “pandemic” of sudden cardiac arrests, cancers or neurodegenerative diseases. It is a hodge-podge of the lot, with no seeming singular cause.

Until now.

All these deaths can be explained in a very clear and concise way. They are all CAUSES OF DEATH SEEN IN THE OLDEST OLD. One only needs think of the final scene of The Godfather III, where Corleone falls over dead from his chair – expected in an individual of advanced age. Not so in a 26-year-old – unless their heart has been “transformed” into that of a nonagenarian.

COVID-19 has been generally regarded, of late, as an Endothelial disease. I have called this SPED (Spike Protein Endothelial Disease). However, I was not satisfied as this being the ultimate cause of all the pathology being observed. Therefore, I endeavored to look deeper, to find what is ACTUALLY causing the pathologies. What I discovered is most alarming.

I believe that STAGE I of Spike Protein Progeria Syndrome (SPPS) is an Endothelial “reaction” to the INVASION of the Spike protein INTO ALL OF THE MAJOR ORGANS. Consider this much like the shock of being submerged in freezing water, or being blasted with fire. There is INSTANTANEOUS damage: inflammation, coagulation and all that accompanies an insult to the Endothelium.

However, once the Spike Protein has INVADED the Endothelium of all the major organs, it then PROCEEDS TO INDUCE MISTRANSLATION OF mRNA IN EACH ORGAN.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses
https://www.sciencedirect.com/science/article/pii/S0092867420313106

System-wide transcriptome damage and tissue identity loss in COVID-19 patients
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784611/

Yet, what does this mean? It means, I believe, that STAGE II of SPPS is the PREMATURE AGING of all organs via INDUCED MISTRANSLATIONS OF PROTEINS ESSENTIAL FOR THAT ORGAN’S FUNCTIONING.

Here, we show that Rps9 D95N knock-in mice exhibit reduced life span and a premature onset of numerous aging-related phenotypes, such as reduced weight, chest deformation, hunchback posture, poor fur condition, and urinary syndrome, together with lymphopenia, increased levels of reactive oxygen species–inflicted damage, accelerated age-related changes in DNA methylation, and telomere attrition.

In humans, numerous CpG sites show DNA methylation patterns that change with age and retrospective analysis of longitudinal cohort studies have indicated that premature changes in DNA methylation–correlated molecular aging patterns coincide with a significantly increased risk of overall mortality.

In general, the clustering of diseases, known as comorbidities, indicates a common factor. The comorbidities associated with aging, such as frailty, kyphosis, cataract, and skin dystrophia, imply a shared underlying mechanism. Thus, a holistic pathomechanistic view of aging and age-related diseases has to address systems-based rather than tissue- or organ-specific means of explanation. The idea that aging and the aging process may be related to protein synthesis and its accuracy has been an attractive hypothesis for many years, in part because the main contributor to errors in gene expression comes from mRNA translation by the ribosome with an average error rate of 10−4.

Premature aging in mice with error-prone protein synthesis
https://www.science.org/doi/10.1126/sciadv.abl9051

The Wizard is indeed behind the curtain. We are seeing a 26-year-old die. But that 26-year-old has the organs of a 96-year-old. No surprise in rapid cancers, neurodegeneration or sudden cardiac death – for a 96-year-old.

I believe the Spike Protein is acting as a Progeria Drug – delivered via the Endothelium to all organs.

I don’t know, yet, what to do. I am deeply saddened, and numb. No matter what evidence or hypothesis is presented – the band plays on…

And it is playing a funeral march.